董川，男
研究方向
我的研究兴趣集中在结合生物信息学、分子演化和人工智能技术，研究新基因（年轻基因）和必需基因起源和演化相关的生物学问题。
学习与工作经历
2010年9月-2014年7月：德州学院理学学士 本科/理学学士；
2014年9月-2016年7月：电子科技大学理学硕士（985）；
2016年9月-2020年12月：电子科技大学工学博士（985）；
2018年12月-2021年1月：芝加哥大学；
2021年3月-2023年8月：武汉大学重点资助博后（985）；
2023年9月-至今：浙江农林大学。
教学工作
《植物基因组学》、《测序原理和数据分析》
科研项目
2021年中国博士后站前特别资助（主持，18万，结题）
2021年中国博士后面上资助（主持，8万，结题）
2023年国家自然科学基金青年科学基金项目（30万）
2023年浙江农林大学科研发展基金（10万）
论文与专著
1. Chuan Dong, Shengqian Xia, Li Zhang, et al. Subcellular enrichment patterns of new genes in Drosophila evolution[J]. Molecular Biology and Evolution, 2025: msaf038.(发表当年IF>10).
2. Chuan Dong, Ge-Fei Hao, Hong-Li Hua, Shuo Liu, Abraham Alemayehu Labena, Guoshi Chai, Jian Huang, Nini Rao, Feng-Biao Guo*. Anti-CRISPRdb: a comprehensive online resource for anti-CRISPR proteins. Nucleic Acids Research, 2018, 46(D1): D393-D398.(发表当年IF= 16.9).
3. Chuan Dong, Yan-Ting Jin, Hong-Li Hua, Qing-Feng Wen, Sen Luo, Wen-Xin Zheng, Feng-Biao Guo. Comprehensive review of the identification of essential genes using computational methods: focusing on feature implementation and assessment. Briefings in Bioinformatics, 2020, 21(1): 171-181. (发表当年IF=13.994).
4. Jiafeng Yu, Wenwen Jiang, Sen-Bin Zhu, Zhen Liao, Xianghua Dou, Jian Liu, Feng-Biao Guo,Chuan Dong*. Prediction of protein-coding small ORFs in multi-species using integrated sequence-derived features and the random forest model. Methods, 210(1) 2023, 10-19.(通讯作者，发表当年IF=4.7).
5. Chuan Dong, Zhi Zeng, Dong-Kai Pu, Qing-Feng Wen, Shuo Liu, Meng-Ze Du, Yan Sun, Yi-Zhou Gao, Nini Rao, Jian Huang, Feng-Biao Guo. CasLocusAnno: a web-based server for annotating Cas loci and their corresponding (sub) types. FEBS Letters, 2019, 593(18):2646-2654.(发表当年IF=4.1).
6. Chuan Dong, Ya-Zhou Yuan, Fa-Zhan Zhang, Hong-Li Hua, Yuan-Nong Ye, Abraham Alemayehu Labena, Hao Lin, Wei Chen, Feng-Biao Guo. Combining pseudo dinucleotide composition with the Z curve method to improve the accuracy of predicting DNA elements: a case study in recombination spots. Molecular BioSystems, 2016, 12(9): 2893-2900. (IF=3.7).
7. Chuan Dong, Xin Wang, Cong Ma, Zhi Zeng, Dong-Kai Pu, Shuo Liu, Candy-S Wu, Shixin Chen, Zixin Deng, Feng-Biao Guo. Anti-CRISPRdb v2. 2: an online repository of anti-CRISPR proteins including information on inhibitory mechanisms, activities and neighbors of curated anti-CRISPR proteins. Database, 2022, 2022: baac010. (IF=4.776).
8. Feng-Biao Guo,Chuan Dong, Hong-Li Hua, Shuo Liu, Hao Luo, Hong-Wan Zhang, Yan-Ting Jin, Kai-Yue Zhang. Accurate prediction of human essential genes using only nucleotide composition and association information. Bioinformatics, 2017, 33(12): 1758-1764. (IF=6.9).
9. Yuan Huang, Jiahui Chen,Chuan Dong, Dylan Sosa, Shengqian Xia, Yidan Ouyang, Chuanzhu Fan, Dezhu Li, Emily Mortola, Manyuan Long, Joy Bergelson. Species-specific gene duplication inArabidopsis thaliana evolved novel phenotypic effects on morphological traits under strong positive selection. The Plant Cell, 2022, 34(2): 802-817. (IF>11.27).
10. Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong,Chuan Dong, Peter F. Leadlay, Kui Hong, Zixin Deng, Fuling Zhou and Yuhui Sun. Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition[J]. Nature Communications, 2023, 14(1): 612.(IF>14.919).
11. Qing-Feng Wen, Shuo Liu,Chuan Dong, Hai-Xia Guo, Yi-Zhou Gao, Feng-Biao Guo*. Geptop 2.0: an updated, more precise, and faster Geptop server for identification of prokaryotic essential genes. Frontiers in Microbiology, 2019, 10: 1236.(IF=5.64).
12. Chengchi Fang†,Chuan Dong†, Cheng Wang, Fan Xiong, Xiaoni Gan, Liandong Yang, Honghui Zeng, Shunping He*. GageTracker: a tools for dating gene age by micro- and macro- collinearity in a high speed and accuracy. (共同一作，In submission).
联系方式
通讯地址：浙江省杭州市临安区武肃街666号浙江农林大学东湖校区国重楼432
邮 编: 311300
邮 箱：chuand@zafu.edu.cn
