
肖力宏,博士,校特聘教授,博士研究生导师。长期致力于资源植物与经济林木的基因组与功能基因组学和植物逆境应答分子机制及其在陆生植物中的进化研究,在植物逆境应答进化机制、经济林果抗病与品质调控基因挖掘等方面取得一系列创新成果。以第一作者和通讯作者在PNAS、New Phytologist、Plant Communications、Plant Cell & Environment等国际学术刊物发表研究论文16篇,以主要参与者在Cell、PNAS、Nature Communication、Cell Research等国际顶级学术期刊发表研究论文6篇。担任Nature Communication、Plant Physiology等多种国际学术期刊审稿专家。2023年起担任浙江省生物信息学学会第三届理事会理事。
研究方向
1.特色经济林果真菌病害抗性调控分子机制与种质创新
2.特色经济林果重要营养成分关键调控基因挖掘与种质创新
3.资源植物基因组与功能基因组学研究
4.植物逆境应答的分子机制及其进化
学习与工作经历
2017/09—至今 浙江农林大学林业与生物技术学院校特聘教授
2015/06—2017/08中科院上海植物逆境研究中心副研究员,朱建康院士团队
2010/08—2014/10首都师范大学资源环境与旅游学院博士后,何奕騉教授团队
2012/03-2014/07美国密苏里大学农学院/USDA-ARS-PGRU合作研究,Melvin J Oliver教授团队
2007/09—2010/06首都师范大学生命科学学院博士研究生,导师匡廷云院士、何奕騉教授
2003/05-2005/05中科院植物研究所系统与进化中心客座研究,王印政研究员团队
2002/09—2005/06内蒙古大学生命科学学院硕士研究生,导师宝音陶格涛研究员
教学工作
本科:植物学,Botany(留学生)
硕博研究生:植物基因组与功能基因组学前沿,高级植物分子生物学专题
科研项目
1. PpDT1介导的新型ABA信号级联调控小立碗藓极端干旱应答的分子机制,国家自然科学基金2020-2023(主持)
2.调控山核桃坚果重要品质营养性状关键基因的挖掘和功能解析,浙江省自然科学基金重点项目2020-2023(主持)
3.特色经济林重要性状形成与调控,国家重点研发专项子课题2018-2022(参加)
4.(美国)山核桃品质与营养相关基因的挖掘与应用,浙江农林大学科研发展基金2018-2020(主持)
5.小立碗藓干细胞重新编程关键候选基因的功能研究,中国博士后科学基金第五批特别资助2012-2013(主持)
6.小立碗藓干旱胁迫功能基因组、表观组及其耐极端干旱调控机制研究,北京市博士后科研活动经费资助2011-2012(主持)
研究成果
第一作者(#)和/或通讯作者(*)发表论文
1.Xiao L.#,*, Zhao L.#, Cao X.#, Li X, Niu Q., Dang Y., Oliver M.J., He Y. (2025) Surviving dehydration: shutdown–restart dynamics inPhyscomitrium patensavoids the metabolic collapse seen inArabidopsis.New Phytologist. https://doi.org/10.1111/nph.70703
2.Niu Q.#, Zhao L.#, Dang Y., Guo R., Deng K.,Xiao L.*(2025) Bryophyte ELIPs as Evolutionary Guardians: Engineering Chloroplast Resilience and ABA‐Enhanced Drought Tolerance in Crops. Plant, Cell & Environment48(11):7948-7960. https://doi.org/10.1111/pce.70094
3. Deng K.#, Zhang Y.#, Lv S., Zhang C.,Xiao L.*(2025) Decoding Pecan's Fungal Foe: A Genomic Insight intoColletotrichum plurivorumisolate W-6.J. Fungi11(3):203. https://doi.org/10.3390/jof11030203.
4. Lv S.#, Mo Y.#, Deng K., Wang H.#, Xie Z., Guo K., Wang Z., Zhang C.*,Xiao L.*(2023) First report ofFusarium concentricumasa causal agent ofFusariumleaf blotch on pecan (Carya illinoinensis) in Southeast China.Plant Dis.107(8):2549. https://doi.org/10.1094/PDIS-12-22-2810-PDN
5. Zhang Y.#, Liu Y.#, Ma L., Lv S., Zhang C.,Xiao L.* (2023) First report ofColletotrichum plurivorumcausing anthracnose on pecan (Carya illinoinensis) in China.Plant Dis. 107(8):2547. https://doi.org/10.1094/PDIS-12-22-2774-PDN
6. Lv S.#, Zhang Y.#, Zhang C.*,Xiao L.* (2023) First report ofCurvularia muehlenbeckiae, the causal agent ofCurvularialeaf spot on pecan (Carya illinoinensis) in China.Plant Dis. 107(4):1232. https://doi.org/10.1094/PDIS-07-22-1516-PDN
7. Xi J.#, Lv S.#, Zhang W.#, Zhang J.#,*, Wang K., Guo H., Hu J., Yang Y., Wang J., Xia G., Fan G., Wang X.,Xiao L.*(2022) Comparative plastomes ofCaryaspecies provide new insights into the plastomes evolution and maternal phylogeny of the genus.Front. Plant Sci.13:990064. https://doi.org/10.3389/fpls.2022.990064
8. Li X.#, Cao X.#, Li J., Niu Q., Mo Y.,Xiao L.*(2022) Genome-wide characterization of C2H2 zinc-finger gene family provides insight into the mechanisms and evolution of the dehydration-rehydration responses inPhyscomitriumandArabidopsis.Front. Plant Sci.13:953459.https://doi.org/10.3389/fpls.2022.953459
9.Xiao L.#,*, Yu M.#, Zhang Y.#, Hu J., Wang J., Guo H., Zhang H., Guo X., Deng T., Lv S., Li X., Huang J., Fan G.*(2021) Chromosome-scale assembly reveals the asymmetric paleo-subgenomes evolution and targets for accelerating fungal resistance breeding in nut crop, pecan.Plant Communications2(6):100247. https://doi.org/10.1016/j.xplc.2021.100247
10. Huang Y.#,Xiao L.#,*, Zhang Z.†, Zhang R., Wang Z., Huang C., Huang R., Luan Y., Fan T., Wang J., Shen C., Zhang S., Wang X., Randall J., Zheng B., Wu J., Zhang Q., Xia G., Xu C., Chen M., Zhang L., Jiang W., Gao L., Chen Z., Leslie C. A., Grauke L. J., Huang J.*(2019) The genomes of pecan and Chinese hickory provide insights intoCaryaevolution and nut nutrition. GigaScience8(5):1-17. https://doi.org/10.1093/gigascience/giz036
11.Xiao L.*, Yobi A., Koster L. K., He Y., Oliver M. J.(2018) Desiccation tolerance inPhyscomitrella patens: Rate of dehydration and the involvement of endogenous abscisic acid (ABA).Plant, Cell & Environment41(2):275-284. https://doi.org/10.1111/pce.13096
12.Xiao L., Yang G., Zhang L., Yang L., Zhao S., Ji Z., Zhou Q., Hu M., Wang Y., Chen M., Xu Y., Jin H., Xiao X., Hu G., Bao F., Hu Y., Wan P., Li L., Deng X., Kuang T., Xiang C., Zhu J-K.*, Oliver M. J.*, He Y.* (2015) The resurrection genome ofBoea hygrometrica: a blueprint for survival of dehydration.P Natl. Acad. Sci. USA112(18):5833-5837. https://doi.org/10.1073/pnas.1505811112
13.Xiao L., Li Z., Wang R., Wang Y-Z.* (2012) Population differentiation and phylogeographic pattern of a relict species,Conandron ramondioides(Gesneriaceae), revealed from sequence polymorphism and haplotypes of theCYCLOIDEAgene.Journal of Systematics and Evolution50(1):45-57. https://doi.org/10.1111/j.1759-6831.2011.00166.x
14.Xiao L., Zhang L., Yang G., Zhu H., He Y.* (2012) Transcriptome of Protoplasts Reprogrammed into Stem Cells inPhyscomitrella patens.PLoS One7(4):e35961. doi:10.1371/journal.pone.0035961
15.Xiao L., Wang H., Wan P., Kuang T., He Y.* (2011) Genome-wide transcriptome analysis of gametophyte development inPhyscomitrella patens.BMC Plant Biology11(1):177. https://doi.org/10.1186/1471-2229-11-177
16.Xiao L., Wang Y-Z.* (2007) Single nucleotide polymorphisms ofGCYC1(CYCLOIDEA) in Conandron ramondioides(Gesneriaceae) from Southeast China.Plant Systematics and Evolution269:145-157. https://doi.org/10.1007/s00606-007-0592-4
合作发表论文
17. Hu R#., Li X#., Hu Y., Zhang R., Lv Q., Sheng X., Zhao F., Chen Z., Ding Y., Yuan H., Wu X., Xing S., Yan X., Bao F., Wan P.,Xiao L., Wang X., Decker E., van Gessel N., Renault H., Wiedemann G., Horst N.A., Hass F.B., Wihelmsson P.K.I., Ullrich K.K., Neumann E., Lv B., Liang C., Du H., Gao Q., Cheng Z., You H., Xin P., Chu J., Huang C.-H., Liu Y., Dong S. Zhang L., Chen F., Deng L., Duan F., Zhao W., Li K., Li Z., Li X.,, Cui H., Zhang Y.E., Ma C., Zhu R., Jia Y., Wang M., Hasebe M., Fu J., Goffinet B., Ma H., Rensing S., Reske R*., He Y*. (2023)Adaptive evolution of the enigmatic Takakia now facing climate change in Tibet.Cell, 186:3558-3576. http://doi.org/10.1016/j.cell.2023.07.003
18. Miao C.,Xiao L., Hua K., Zou C., Zhao Y., Ray A., Bressan R.A., Zhu J-K.*. (2018) Mutations in a subfamily of abscisic acid receptor genes promote rice growth and productivity.P Natl. Acad. Sci. USA,115(23):6058-6063. https://doi.org/10.1073/pnas.1804774115
19. Zou C., Chen A.,Xiao L., Muller H. M., Ache P., Haberer G., Zhang M., Jia W., Deng P., Huang R., Lang D., Li F., Zhan D., Wu W., Zhang H., Bohm J., Liu R., Shabala S., Hedrich R.*, Zhu J-K.*, Zhang H.*. (2017) A high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value.Cell Research27(11):1327-1340. https://doi.org/10.1038/cr.2017.124
20. Hu R.,Xiao L., Bao F., Li X. He Y.* (2016) Dehydration-responsive features ofAtrichum undulatum.Journal of Plant Research129(5):945-954. https://doi.org/10.1007/s10265-016-0836-x
21. Zou C., Li L., Miki D., Li D., Tang Q.,Xiao L., Rajput S., Deng P., Peng L., Jia W., Huang R., Zhang M., Sun Y., Hu J., Fu X., Schnable P. S., Chang C., Li F., Zhang H., Feng B., Zhu X., Liu R., Schnable J.C., Zhu J.-K.* Zhang H.* (2019) The genome of broomcorn millet.Nature Communication10:436. https://doi.org/10.1038/s41467-019-08409-5
22. Bai S., Li M, Yao T., Wang H., Zhang Y.,Xiao L., Wang J., Zhang Z., Hu Y., Liu W., He Y.* (2012) Nitric Oxide Restraint Root Growth by DNA Damage Induced Cell Cycle Arrest in Arabidopsis thaliana.Nitric Oxide-Biology and Chemistry26(1):54-60. https://doi.org/10.1016/j.niox.2011.12.001
授权发明专利:美国山核桃CiIGLR3.6-4和CiIGLR3.6-5基因及其应用(ZL 2021 1 0902687.8;发明人,排名:1/3)
硕士研究生招生方向:林学、植物学(分子生物学)、生物化学与分子生物学、林业(资源植物利用)
优先考虑对本实验室研究方向有浓厚兴趣、有志从事科学研究学生,表现优异者推荐到国内外著名实验室交流学习,截至目前本实验室所有毕业研究生均以第一作者在中科院2区以上SCI期刊发表研究论文取得学位。
(长期招优秀博士后研究人员和科研助理,特别欢迎有生物信息学分析和分子生物学基础到本实验室学习和工作)
电子邮箱:xiaolh@zafu.edu.cn
通讯地址:浙江省杭州市临安区武肃街666号智能楼S202,邮编:311300
个人主页
https://sky.zafu.edu.cn/info/1201/11842.htm
https://sky.zafu.edu.cn/info/1222/10927.htm
https://www.researchgate.net/profile/Lihong-Xiao